BACE2 抗体 (C-Term)
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北京 101111
Quick Overview for BACE2 抗体 (C-Term) (ABIN6990329)
抗原
See all BACE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- BACE2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- BACE2 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human BACE2. The immunogen is located within the last 50 amino acids of BACE2.
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亚型
- IgG
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anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 230-396) antibody
BACE2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 242-502) antibodyBACE2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 156-407) antibodyBACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 84-157) antibodyBACE2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 44-59) antibodyBACE2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (C-Term) antibodyBACE2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) antibodyBACE2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 1-9 unconjugated Recombinant Antibody
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 336-365) antibodyBACE2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 101-200) antibodyBACE2 适用: 大鼠 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 306-395) antibodyBACE2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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BACE2 antibody can be used for detection of BACE2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BACE2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BACE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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别名
- BACE2
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背景
- BACE2 Antibody: Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). BACE/Asp2 is a novel transmembrane aspartic protease and co-localizes with APP. A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1. BACE2 also cleaves APP at b-site and at a different site within Abeta. BACE2 locates on chromosome 21q22.3, the so-called 'Down critical region', suggesting that BACE2 and Abeta may also contribute to the pathogenesis of Down syndrome.
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分子量
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Predicted: 57 kDa
Observed: 57 kDa -
基因ID
- 25825
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UniProt
- Q9Y5Z0
抗原
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