CCR8 抗体 (AA 170-220)
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北京 101111
Quick Overview for CCR8 抗体 (AA 170-220) (ABIN6990287)
抗原
See all CCR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-220
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纯化方法
- CCR8 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CCR8 antibody was raised against a 19 amino acid peptide near the center of human CCR8. The immunogen is located within amino acids 170 - 220 of CCR8.
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亚型
- IgG
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应用备注
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CCR8 antibody can be used for detection of CCR8 by Western blot 0.5 μ,g/mL. An approximately 50 kDa band can be detected.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CCR8 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CCR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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别名
- CCR8
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背景
- CCR8 Antibody: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
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分子量
- 50 kDa
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基因ID
- 1237
抗原
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