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CIDEA 抗体 (C-Term)

This anti-CIDEA antibody is a 兔 多克隆 antibody detecting CIDEA in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6990284
发货至: 中国

Quick Overview for CIDEA 抗体 (C-Term) (ABIN6990284)

抗原

See all CIDEA 抗体
CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

适用

  • 28
  • 23
  • 16
人, 小鼠

宿主

  • 45
  • 3
  • 1

克隆类型

  • 48
  • 1
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CIDEA antibody is un-conjugated

应用范围

  • 29
  • 20
  • 13
  • 13
  • 9
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 8
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    • 1
    • 1
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    • 1
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    C-Term

    特异性

    It has no cross activity to CIDE-B.

    纯化方法

    CIDE-A Antibody is affinity chromatography purified via peptide column.

    免疫原

    CIDE-A antibody was raised against an 18 amino acid peptide near the carboxy terminus of mouse CIDE-A. The immunogen is located within the last 50 amino acids of CIDE-A.

    亚型

    IgG
  • 应用备注

    CIDE-A antibody can be used for detection of CIDE-A by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CIDE-A Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    CIDE-A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

    别名

    CIDE-A

    背景

    CIDE-A Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.

    分子量

    25 kDa

    基因ID

    1149

    NCBI登录号

    NP_031728

    UniProt

    O60543
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