AIF 抗体 (AA 500-550)
Quick Overview for AIF 抗体 (AA 500-550) (ABIN6990274)
抗原
See all AIF (AIFM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 500-550
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特异性
- At least five isoforms of AIF are known to exist, this antibody will detect all isoforms except isoform 5.
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纯化方法
- AIF Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-AIF antibody was raised against a peptide corresponding to 15 amino acids near the center of human AIF. The immunogen is located within amino acids 500-550 of AIF.
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亚型
- IgG
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibodyAIFM1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-322) antibodyAIFM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibodyVerified AIFM1 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 334-613) antibodyAIFM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 183-195) antibodyVerified AIFM1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-612) antibodyAIFM1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 1-613) antibodyAIFM1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 1-613) antibodyAIFM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibodyAIFM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1-2 μ,g/mL, IHC-P: 10 μ,g/mL.
Antibody validated: Western Blot in human, mouse, and rat samples, Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- AIF Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- AIF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
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别名
- AIF
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背景
- AIF Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.
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分子量
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Predicted: 67 kDa
Observed: 68 kDa -
基因ID
- 9131
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UniProt
- O95381
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
抗原
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