FLIP 抗体 (C-Term)
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北京 101111
Quick Overview for FLIP 抗体 (C-Term) (ABIN6990261)
抗原
See all FLIP (CFLAR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Antibody recognizes the FLIPa only.
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纯化方法
- FLIP Antibody is Antibody is DEAE purified.
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免疫原
- FLIP antibody was raised against a peptide corresponding to amino acids near the C-terminus of human FLIPaFLIPl form. The immunogen is located within the last 50 amino acids of FLIP.
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亚型
- IgG
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anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 100-251) antibody
CFLAR 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A3D12 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 178-277) antibodyCFLAR 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 161-480) antibodyCFLAR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 1-250) antibodyCFLAR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 191-209) antibodyCFLAR 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 178-277) antibodyCFLAR 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1G1 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 7-100) antibodyCFLAR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 401-480) antibodyCFLAR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (N-Term) antibodyCFLAR 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 43-281) antibodyCFLAR 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flip antibody can be used for detection of FLIP by Western blot at 1 μ,g/mL. A 55 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- FLIP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- FLIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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别名
- FLIP
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背景
- FLIP Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP3-7. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors. Four splice variants of c-FLIPs have been identified and termed FLIPalpha, beta, gamma, and delta, respectively.
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分子量
- 55 kDa
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基因ID
- 8837
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UniProt
- O15519
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途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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