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GFRA2 抗体 (AA 360-410)

GFRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990251
发货至: 中国
  • 抗原 See all GFRA2 抗体
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 360-410
    适用
    • 50
    • 25
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 47
    • 2
    • 1
    • 1
    克隆类型
    • 49
    • 1
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GFRA2 antibody is un-conjugated
    应用范围
    • 47
    • 23
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    GFR alpha 2 Antibody is Ion exchange chromatography purified.
    免疫原
    GFR alpha 2 antibody was raised against a 15 amino acid peptide near the center of human GFR alpha 2. The immunogen is located within amino acids 360 - 410 of GFR alpha 2.
    亚型
    IgG
    Top Product
    Discover our top product GFRA2 Primary Antibody
  • 应用备注
    GFR alpha 2 antibody can be used for detection of GFR alpha 2 by Western blot at 1 μ,g/mL. A 52 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    GFR alpha 2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    GFR alpha 2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    别名
    GFR alpha 2 (GFRA2 产品)
    别名
    GDNFRB antibody, NRTNR-ALPHA antibody, NTNRA antibody, RETL2 antibody, TRNR2 antibody, Retl2 antibody, NTNRALPHA antibody, ntnra antibody, retl2 antibody, trnr2 antibody, gdnfrb antibody, nrtnr-alpha antibody, gfra2 antibody, GDNF family receptor alpha 2 antibody, glial cell line derived neurotrophic factor family receptor alpha 2 antibody, GDNF family receptor alpha 2a antibody, GFRA2 antibody, Gfra2 antibody, gfra2 antibody, gfra2a antibody
    背景
    GFR alpha 2 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα,-2 recently. GFRα,-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRα,-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
    分子量
    Predicted: 51 kDa

    Observed: 52 kDa
    基因ID
    2675
    UniProt
    O00451
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