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GFRA2 抗体 (AA 360-410)

This anti-GFRA2 antibody is a 兔 多克隆 antibody detecting GFRA2 in WB, ELISA 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990251
发货至: 中国

Quick Overview for GFRA2 抗体 (AA 360-410) (ABIN6990251)

抗原

See all GFRA2 抗体
GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

适用

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人, 小鼠, 大鼠

宿主

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  • 2
  • 1
  • 1

克隆类型

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  • 1
多克隆

标记

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This GFRA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 7
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    AA 360-410

    纯化方法

    GFR alpha 2 Antibody is Ion exchange chromatography purified.

    免疫原

    GFR alpha 2 antibody was raised against a 15 amino acid peptide near the center of human GFR alpha 2. The immunogen is located within amino acids 360 - 410 of GFR alpha 2.

    亚型

    IgG
  • 应用备注

    GFR alpha 2 antibody can be used for detection of GFR alpha 2 by Western blot at 1 μ,g/mL. A 52 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    GFR alpha 2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    GFR alpha 2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

    别名

    GFR alpha 2

    背景

    GFR alpha 2 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα,-2 recently. GFRα,-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRα,-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

    分子量

    Predicted: 51 kDa

    Observed: 52 kDa

    基因ID

    2675

    UniProt

    O00451
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