MAP3K14 抗体 (C-Term)
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北京 101111
Quick Overview for MAP3K14 抗体 (C-Term) (ABIN6990248)
抗原
See all MAP3K14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- NIK Antibody is affinity chromatography purified via peptide column.
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免疫原
- NIK antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NIK. The immunogen is located within the last 50 amino acids of NIK.
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亚型
- IgG
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应用备注
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NIK antibody can be used for detection of NIK by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NIK Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NIK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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别名
- NIK
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背景
- NIK Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFα, LPS and mitogens. A serine/threonine protein kinase which mediates NF-κ,B activation by IL-1, TNFα, and CD95 was identified recently and designated NIK (for NF-κ,B inducing kinase). NIK is an activator of Iκ,B kinase alpha and beta (IKKα, and IKKβ,). Therefore, NIK is a key molecule in the NF-κ,B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.
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分子量
- Predicted: 104 kDa
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基因ID
- 9020
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UniProt
- Q99558
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途径
- NF-kappaB Signaling, TCR Signaling
抗原
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