Neurturin 抗体 (C-Term)
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Quick Overview for Neurturin 抗体 (C-Term) (ABIN6990244)
抗原
See all Neurturin (NRTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Neurturin Antibody is affinity chromatography purified via peptide column.
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免疫原
- Neurturin antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Neurturin. The immunogen is located within the last 50 amino acids of Neurturin.
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亚型
- IgG
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anti-Neurturin (NRTN) (AA 151-197) antibody
NRTN 适用: 人, 小鼠, 犬, 小鸡 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neurturin (NRTN) antibodyNRTN 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurturin (NRTN) (C-Term) antibodyVerified NRTN 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Neurturin (NRTN) (C-Term) antibodyVerified NRTN 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neurturin (NRTN) (AA 178-193) antibodyNRTN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurturin (NRTN) antibodyNRTN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D12 unconjugated
anti-Neurturin (NRTN) (AA 178-193) antibodyNRTN 适用: 人 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neurturin antibody can be used for detection of neurturin by Western blot. An approximate 14 kDa band of the full length recombinant NTN was detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Neurturin Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Neurturin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Neurturin (NRTN)
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别名
- Neurturin
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背景
- Neurturin Antibody: Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently and termed GDNFRβ, Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα,-2 recently. NTN binds to and forms a complex with GFRα,-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.
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分子量
- 14 kDa
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基因ID
- 4902
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NCBI登录号
- NP_004549
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UniProt
- Q99748
抗原
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