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CCR5 抗体 (N-Term)

CCR5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990239
发货至: 中国
  • 抗原 See all CCR5 抗体
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    抗原表位
    • 16
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    N-Term
    适用
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    宿主
    • 101
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    克隆类型
    • 104
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    多克隆
    标记
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    This CCR5 antibody is un-conjugated
    应用范围
    • 92
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    CCR5 Antibody is affinity chromatography purified via peptide column.
    免疫原
    CCR5 antibody was raised against a 15 amino acid peptide near the amino terminus of human CCR5. The immunogen is located within the first 50 amino acids of CCR5.
    亚型
    IgG
    Top Product
    Discover our top product CCR5 Primary Antibody
  • 应用备注
    CCR5 antibody can be used for Western blot at 1 μ,g/mL. CCR5 antibody can also detect CCR5 by immunohistochemistry at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    CCR5 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    CCR5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    别名
    CCR5 (CCR5 产品)
    别名
    CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
    背景
    CCR5 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.
    分子量
    Predicted: 39 kDa

    Observed: 40 kDa
    基因ID
    1234
    UniProt
    P51681
    途径
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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