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PD-L1 抗体 (Extracellular Domain)

Name: PD-L1 抗体 (Extracellular Domain)
Brand: antibodies-online
SKU: ABIN6990233
Availability: OutOfStock

This 小鼠单克隆 anti-PD-L1 antibody (Clone 6H10) specifically detects PD-L1 in WB, ELISA, ICC, IF 和 IHC (p). The antibody is reactive with 人和小鼠 samples.

产品编号 ABIN6990233

发货至: 中国

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中国
北京 101111

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Quick Overview for PD-L1 抗体 (Extracellular Domain) (ABIN6990233)

抗原

See all PD-L1 抗体

PD-L1 (CD274 (PD-L1))

适用

人, 小鼠

宿主

小鼠

克隆类型

单克隆

标记

This PD-L1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

6H10

Discover our top product PD-L1 Primary Antibody

抗原表位
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29

16

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10

8

7

7

7

6

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4

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2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Extracellular Domain

特异性

PD-L1 Antibody has no cross-reactivity to PD-L2.

纯化方法

PD-L1 Antibody is supplied as protein A purified IgG1.

免疫原

Anti-PD-L1 antibody was raised against the extracellular domain of human PD-L1.

亚型

IgG1
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 适用: 人 WB, FACS, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) antibody
PD-L1 适用: 人 IHC 宿主: 兔 Monoclonal 711R unconjugated Recombinant Antibody

应用备注

WB: 0.25 - 4 μ,g/mL, IF: 2 μ,g/mL, IHC-P: 5 μ,g/mL, ICC: 1 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry, Immunocytochemistry and Immunofluorescence in human samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PD-L1 Antibody is supplied in PBS containing 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

PD-L1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

PD-L1 (CD274 (PD-L1))

别名

PDL1

背景

PD-L1 plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3). Through a yet unknown activating receptor, it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4).

分子量

Predicted: 33kD

Observed: 37kD kDa

基因ID

29126

NCBI登录号

NP_054862

UniProt

Q9NZQ7

途径

Cancer Immune Checkpoints