LIN28A 抗体 (C-Term)
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北京 101111
Quick Overview for LIN28A 抗体 (C-Term) (ABIN6990210)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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特异性
- At least two isoforms of Lin28 are known to exist, this antibody will detect both. Lin28 antibody will not cross-react with Lin28 Homolog B.
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纯化方法
- Lin28 Monoclonal Antibody is affinity chromatography purified via peptide column.
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免疫原
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Mouse monoclonal Lin28 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Lin28.
The immunogen is located within the last 50 amino acids of Lin28. -
亚型
- IgG2b
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应用备注
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Lin28 antibody can be used for detection of Lin28 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Lin28 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Lin28 Monoclonal antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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别名
- Lin28
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背景
- Lin28 Monoclonal Antibody: Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
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分子量
- Predicted: 23 kDa
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基因ID
- 79727
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NCBI登录号
- NP_078950
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UniProt
- Q9H9Z2
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途径
- Stem Cell Maintenance
抗原
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