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LIN28A 抗体 (C-Term)

This anti-LIN28A antibody is a 小鼠 单克隆 antibody detecting LIN28A in WB 和 ELISA. Suitable for 人.
产品编号 ABIN6990210
发货至: 中国

Quick Overview for LIN28A 抗体 (C-Term) (ABIN6990210)

抗原

See all LIN28A 抗体
LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LIN28A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1G9H9
  • 抗原表位

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    C-Term

    特异性

    At least two isoforms of Lin28 are known to exist, this antibody will detect both. Lin28 antibody will not cross-react with Lin28 Homolog B.

    纯化方法

    Lin28 Monoclonal Antibody is affinity chromatography purified via peptide column.

    免疫原

    Mouse monoclonal Lin28 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Lin28.
    The immunogen is located within the last 50 amino acids of Lin28.

    亚型

    IgG2b
  • 应用备注

    Lin28 antibody can be used for detection of Lin28 by Western blot at 0.5 - 1 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Lin28 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Lin28 Monoclonal antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

    别名

    Lin28

    背景

    Lin28 Monoclonal Antibody: Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

    分子量

    Predicted: 23 kDa

    基因ID

    79727

    NCBI登录号

    NP_078950

    UniProt

    Q9H9Z2

    途径

    Stem Cell Maintenance
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