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BIM 抗体 (AA 2-198)

This anti-BIM antibody is a 小鼠 单克隆 antibody detecting BIM in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6990187
发货至: 中国

Quick Overview for BIM 抗体 (AA 2-198) (ABIN6990187)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

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人, 小鼠

宿主

  • 110
  • 7
  • 3
  • 1
小鼠

克隆类型

  • 95
  • 26
单克隆

标记

  • 69
  • 9
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  • 2
  • 1
  • 1
  • 1
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This BIM antibody is un-conjugated

应用范围

  • 82
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  • 5
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  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

1C2C8
  • 抗原表位

    • 15
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 2-198

    纯化方法

    Bim Monoclonal Antibody is immunoaffinity chromotography purified IgG.

    免疫原

    Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.

    亚型

    IgG1
  • 应用备注

    Bim antibody can be used for detection of Bim by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Bim Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Bim monoclonal antibody can be stored at -20°C, stable for one year.
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    别名

    Bim

    背景

    Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

    基因ID

    10018

    NCBI登录号

    NP_619527

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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