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Hemagglutinin 抗体 (AA 17-338)

This anti-Hemagglutinin antibody is a 小鼠 单克隆 antibody detecting Hemagglutinin in ELISA 和 WB. Suitable for Influenza A Virus H5N1.
产品编号 ABIN6990181
发货至: 中国

Quick Overview for Hemagglutinin 抗体 (AA 17-338) (ABIN6990181)

抗原

See all Hemagglutinin (HA) 抗体
Hemagglutinin (HA)

适用

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Influenza A Virus H5N1

宿主

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小鼠

克隆类型

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单克隆

标记

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This Hemagglutinin antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)

克隆位点

4E10C10
  • 抗原表位

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    AA 17-338

    纯化方法

    Hemagglutinin Monoclonal Antibody is Protein A purified.

    免疫原

    Recombinant protein corresponding to amino acids 17 - 338 of H5 HA1.

    亚型

    IgG1, IgG2b
  • 应用备注

    Hemagglutinin antibody can be used for detection of H5 HA1 by Western blot at 2.5µg/mL. Hemagglutinin antibody also specifically recognizes Avian H5N1 influenza virus at 2 µg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Hemagglutinin Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Hemagglutinin monoclonal antibody can be stored at -20°C, stable for one year.
  • 抗原

    Hemagglutinin (HA)

    别名

    Hemagglutinin

    物质类

    Influenza Protein

    背景

    Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, but it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with host cell surface proteins containing oligosaccharides with terminal sialyl residues. Its extracellular region has two domains (HA1 and HA2), HA1 is cleaved from the main hemagglutinin protein by the host immune system. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. This more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the efficiency of this type of transmission is low. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.

    UniProt

    Q692M2
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