PUMA 抗体 (AA 76-170)
-
- 抗原 See all PUMA (BBC3) 抗体
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
-
抗原表位
- AA 76-170
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This PUMA antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- PUMA Monoclonal Antibody is immunoaffinity chromotography purified IgG.
- 免疫原
- Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.
- 克隆位点
- 2A9G5
- 亚型
- IgG1
- Top Product
- Discover our top product BBC3 Primary Antibody
-
anti-BCL2 Binding Component 3 (BBC3) antibody
BBC3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibodyBBC3 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibodyBBC3 适用: 人, 大鼠, Pig WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibodyBBC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PE)BBC3 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal PE
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PerCP)BBC3 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal PerCP
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB01353 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody (Biotin)BBC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibodyBBC3 适用: 人, 小鼠 WB, FACS, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
PUMA antibody can be used for detection of PUMA by Western blot at 2.5 to 5 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PUMA Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- PUMA monoclonal antibody can be stored at -20°C, stable for one year.
-
- 抗原
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- 别名
- PUMA (BBC3 产品)
- 别名
- BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
- 背景
- PUMA Monoclonal Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMAα, and PUMAβ,. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
- 基因ID
- 27113
- UniProt
- Q9BXH1
- 途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity
-
