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DC-SIGN/CD209 抗体

This anti-DC-SIGN/CD209 antibody is a 小鼠 单克隆 antibody detecting DC-SIGN/CD209 in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN6990166
发货至: 中国

Quick Overview for DC-SIGN/CD209 抗体 (ABIN6990166)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5D7
  • 纯化方法

    DC-SIGN Monoclonal Antibody is immunoaffinity chromotography purified IgG.

    免疫原

    A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN.

    亚型

    IgG1
  • 应用备注

    DC-SIGN antibody can be used for detection of DC-SIGN in Western Blot at 1 - 2 μ,g/mL and in immunohistochemistry at 5 - 10 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    DC-SIGN Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    DC-SIGN monoclonal antibody can be stored at -20°C, stable for one year.
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    DC-SIGN

    背景

    DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

    分子量

    Predicted: 44 kDa

    Observed: 47 kDa

    基因ID

    30835

    UniProt

    Q9NNX6
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