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LY96 抗体 (C-Term)

The 兔 多克隆 anti-LY96 antibody is suitable to detect LY96 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC (p) 和 IF.
产品编号 ABIN6990125
发货至: 中国
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Quick Overview for LY96 抗体 (C-Term) (ABIN6990125)

抗原

See all LY96 抗体
LY96 (Lymphocyte Antigen 96 (LY96))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 41
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多克隆

标记

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This LY96 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    纯化方法

    MD-2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-MD-2 antibody was raised against a peptide corresponding to 13 amino acids near the center of human MD-2. The immunogen is located within the last 50 amino acids of MD-2.

    亚型

    IgG
  • 应用备注

    WB: 0.5-1 μ,g/mL, IHC: 2-2.5 μ,g/mL, IF: 10-20 μ,g/mL.

    Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in human and rat samples, Immunofluorescence in human and rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MD-2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MD-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    LY96 (Lymphocyte Antigen 96 (LY96))

    别名

    MD-2

    背景

    MD-2 Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2, e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

    分子量

    Predicted: 19kD

    Observed: 26 kD (Post-modification: 2 N-linked glycosylations) kDa

    基因ID

    23643

    NCBI登录号

    NP_056179

    UniProt

    Q9Y6Y9

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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