RAC1+CDC42 (pSer71) 抗体
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北京 101111
Quick Overview for RAC1+CDC42 (pSer71) 抗体 (ABIN6989963)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer71
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic phospho-Peptide corresponding to residues surrounding Ser71 of human CDC42.
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亚型
- IgG
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anti-RAC1+CDC42 (AA 38-87) antibody
适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- RAC1+CDC42
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背景
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Synonyms: CDC42Hs antibody, Cell division cycle 42 antibody, G25K antibody, MIG5 antibody, Migration inducing gene 5 antibody, p21 Rac1 antibody, Ras like protein TC25 antibody, Small GTP binding protein Cdc42 antibody, TC25 antibody
Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].
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基因ID
- 998
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UniProt
- P60953
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途径
- WNT signaling
抗原
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