PLK1 抗体 (pThr210)
Quick Overview for PLK1 抗体 (pThr210) (ABIN6989959)
抗原
See all PLK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pThr210
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic phospho-Peptide corresponding to residues surrounding Thr210 of human PLK1.
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亚型
- IgG
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应用备注
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WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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别名
- PLK1
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背景
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Synonyms: Cell cycle regulated protein kinase antibody, PLK 1 antibody, PLK antibody, PLK-1 antibody, plk1 antibody, PLK1_HUMAN antibody, Polo like kinase 1 antibody, Polo-like kinase 1 antibody, Serine/threonine protein kinase 13 antibody, Serine/threonine protein kinase PLK1 antibody, Serine/threonine-protein kinase 13 antibody, Serine/threonine-protein kinase PLK1 antibody, STPK 13 antibody, STPK13 antibody
Background: PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
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基因ID
- 5347
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UniProt
- P53350
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途径
- Cell Division Cycle, M Phase
抗原
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