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beta Catenin 抗体

This anti-beta Catenin antibody is a 兔 多克隆 antibody detecting beta Catenin in WB, IHC, FACS, IHC (p) 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6989907
发货至: 中国

Quick Overview for beta Catenin 抗体 (ABIN6989907)

抗原

See all beta Catenin (CATNB) 抗体
beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This beta Catenin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 650-750 of human beta-catenin (NP_001895.1).

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IP(1-2 μg)
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    别名

    beta-catenin

    背景

    Synonyms: CTNNB,MRD19,armadillo,beta Catenin,CTNNB1

    Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

    基因ID

    1499

    UniProt

    P35222

    途径

    Peptide Hormone Metabolism
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