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CDK8 抗体

This anti-CDK8 antibody is a 兔 多克隆 antibody detecting CDK8 in WB 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6989759
发货至: 中国

Quick Overview for CDK8 抗体 (ABIN6989759)

抗原

See all CDK8 抗体
CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

适用

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人, 小鼠, 大鼠

宿主

  • 76
  • 4
  • 1

克隆类型

  • 68
  • 13
多克隆

标记

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This CDK8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 365-464 of human CDK8 (NP_001251.1).

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IP(1-2 μg)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

    别名

    CDK8

    背景

    Synonyms: CDK8,K35

    Background: This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

    基因ID

    1024

    UniProt

    P49336

    途径

    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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