kappa Light Chain 抗体
Quick Overview for kappa Light Chain 抗体 (ABIN6989724)
抗原
See all kappa Light Chain 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Full length native human IgG.
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亚型
- IgG
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anti-kappa Light Chain antibody (FITC)
适用: 人 FACS 宿主: 小鼠 Monoclonal A8B5 FITC
anti-kappa Light Chain antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal TB28-2 PE
anti-kappa Light Chain antibody适用: 人 FACS, IHC (p), ELISA, IHC (fro) 宿主: 小鼠 Monoclonal A8B5 unconjugated
anti-kappa Light Chain antibody适用: 人 FACS, WB, IHC (p), ELISA, IP, ICC 宿主: 小鼠 Monoclonal MEM-09 unconjugated
anti-kappa Light Chain antibody适用: 人 FACS, WB 宿主: 小鼠 Monoclonal TB28-2 unconjugated
anti-kappa Light Chain antibody (PE)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal TB 28-2 PE
anti-kappa Light Chain antibody (Biotin)适用: 人 FACS 宿主: 小鼠 Monoclonal TB28-2 Biotin
anti-kappa Light Chain (AA 47-63), (N-Term) antibody适用: 人 IHC (p) 宿主: 兔 Monoclonal A21-Y unconjugated
anti-kappa Light Chain antibody (APC)适用: 人 FACS 宿主: 小鼠 Monoclonal TB28-2 APC
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- kappa Light Chain
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背景
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Synonyms: Kappa Light Chain, IGKC, HCAK 1, HCAK1, Ig kappa chain C region, IGKC, Immunoglobulin kappa constant, Immunoglobulin kappa constant region, Immunoglobulin kappa light chain, Kappa 1 immunoglobulin light chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809, Human Ig/L-Chain Kappa, IGKC_HUMAN.
Background: Immunoglobulins belong to a group of related glyco proteins which make up 20 % of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit, while, IgM is a pen tamer. IgA may also form polymers.
Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83. -
基因ID
- 3514
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UniProt
- P01834
抗原
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