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CD35 抗体

This anti-CD35 antibody is a 兔 单克隆 antibody detecting CD35 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN6989711
发货至: 中国

Quick Overview for CD35 抗体 (ABIN6989711)

抗原

See all CD35 (CR1) 抗体
CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

适用

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宿主

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克隆类型

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单克隆

标记

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This CD35 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

3H19
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide corresponding to the extracellular domain of human CD35.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

    别名

    CD35

    背景

    Synonyms: C3 binding protein antibody, C3b/C4b receptor antibody, C3BR antibody, C4BR antibody, CD 35 antibody, CD35 antibody, CD35 antigen antibody, complement component (3b/4b) receptor 1 (Knops blood group) antibody, complement component (3b/4b) receptor 1 including Knops blood group system antibody, Complement component receptor 1 antibody, Complement receptor 1 antibody, Complement receptor type 1 antibody, CR 1 antibody, CR1 antibody, CR1_HUMAN antibody, KN antibody, Knops blood group antigen antibody

    Background: This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.

    基因ID

    1378

    UniProt

    P17927

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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