Recombinant CHMP2B 抗体
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北京 101111
Quick Overview for Recombinant CHMP2B 抗体 (ABIN6989680)
抗原
See all CHMP2B 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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原理
- CHMP2B Recombinant Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic Peptide within Human CHMP2B.
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亚型
- IgG
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应用备注
- WB(1:300-5000), IP(1:20-100), Flow-Cyt(1:200-400), ICC/IF(1:50-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
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别名
- CHMP2B
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背景
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Synonyms: ALS17 antibody, Charged multivesicular body protein 2b antibody, CHM2B_HUMAN antibody, CHMP family, member 2B antibody, CHMP2.5 antibody, CHMP2b antibody, Chromatin modifying protein 2b antibody, Chromatin-modifying protein 2b antibody, DMT1 antibody, hVps2-2 antibody, Vacuolar protein sorting 2, yeast, homolog of, B antibody, Vacuolar protein sorting 2-2 antibody, Vacuolar protein sorting-associated protein 2-2 antibody, VPS2 homolog B antibody, Vps2-2 antibody, VPS2B antibody
Background: The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
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基因ID
- 25978
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UniProt
- Q9UQN3
抗原
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