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EWSR1 抗体

This anti-EWSR1 antibody is a 兔 单克隆 antibody detecting EWSR1 in WB, IHC, IHC (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6989630
发货至: 中国

Quick Overview for EWSR1 抗体 (ABIN6989630)

抗原

See all EWSR1 抗体
EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

适用

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人, 小鼠, 大鼠

宿主

  • 60
  • 10
  • 2
  • 1

克隆类型

  • 63
  • 10
单克隆

标记

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  • 4
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  • 2
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  • 2
  • 1
  • 1
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This EWSR1 antibody is un-conjugated

应用范围

  • 63
  • 28
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  • 4
  • 1
  • 1
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

4G8
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic Peptide within N terminal human EWSR1/EWS.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

    别名

    EWSR1/EWS

    背景

    Synonyms: bK984G1.4 antibody, bK984G1.4 Ewing sarcoma breakpoint region 1 protein antibody, Ewing sarcoma breakpoint region 1 antibody, Ewing sarcoma breakpoint region 1 protein antibody, Ewings sarcoma EWS Fli1 type 1 oncogene antibody, EWS antibody, EWS oncogene antibody, EWS RNA binding protein 1 antibody, EWS_HUMAN antibody, EWSR 1 antibody, Ewsr1 antibody, EWSR1 protein antibody, RNA binding protein EWS antibody, RNA-binding protein EWS antibody

    Background: EWS is a nuclear RNA-binding protein. As a result of chromosome translocation, the EWS gene is fused to a variety of transcription factors, including ATF-1 in human neoplasias. In the Ewing family of tumors, the N-terminal domain of EWS is fused to the DNA-binding domain of various ETS transcription factors, including Fli-1, Erg, ETV1, E1AF and FEV. The EWS/Fli-1 chimeric protein acts as a more potent transcriptional activator than Fli-1 and can promote cell transformation. Two functional regions have been identified in EWS, an amino-terminal region (domain A), that has little transactivation activity but transforms efficiently when fused to Fli-1, and a distal region (domain B), which shows transactivation activity but transforms less efficiently when fused to Fli-1.

    基因ID

    2130

    UniProt

    Q01844
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