CD34 抗体
Quick Overview for CD34 抗体 (ABIN6989467)
抗原
See all CD34 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 犬, 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein G.
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免疫原
- Recombinant human CD34
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亚型
- IgG
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应用备注
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FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CD34
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别名
- CD34
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背景
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Synonyms: CD34 antigen, CD34 Molecule, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, CD34_HUMAN.
Background: The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
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基因ID
- 947
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UniProt
- P28906
抗原
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