DVL1 抗体 (AA 21-100) (PE)
Quick Overview for DVL1 抗体 (AA 21-100) (PE) (ABIN6988150)
抗原
See all DVL1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 21-100
- 
                                            交叉反应
- 人, 小鼠, 大鼠
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human DVL1
- 
                                            亚型
- IgG
 
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- 
    - 
                                            应用备注
- FCM 1:20-100
- 
                                            限制
- 仅限研究用
 
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- 
    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 
                                            有效期
- 12 months
 
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    - DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
- 
                                            别名
- DVL1
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                                            背景
- 
                        Synonyms: DVL, DVL1L1, DVL1P1, Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL1 Background: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ). 
- 
                                            基因ID
- 1855
- 
                                            UniProt
- O14640
- 
                                            途径
- WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
 抗原
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