NOS2 抗体 (AA 1051-1153) (HRP)
Quick Overview for NOS2 抗体 (AA 1051-1153) (HRP) (ABIN6987673)
抗原
See all NOS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1051-1153
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human iNos/Nos-2
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亚型
- IgG
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anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 14-100) antibody
NOS2 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibodyNOS2 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 43-213) antibodyNOS2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 518-694) antibodyNOS2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (Thr177) antibodyNOS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (C-Term) antibodyNOS2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 500-730) antibodyNOS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 830-860) antibodyNOS2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18210 unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibodyNOS2 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibodyNOS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
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别名
- iNos/Nos-2,
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背景
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Synonyms: i NOS, Nitric Oxide Synthase, Inducible, HEP NOS, Hepatocyte NOS, HEPNOS, Inducible nitric oxide synthase, Inducible NO synthase, Inducible NOS, INOS,I-NOS, Inosl, MAC NOS, Macrophage NOS, Nitric oxide synthase 2 inducible macrophage, Nitric oxide synthase 2A (inducible hepatocytes), Nitric oxide synthase inducible, NOS 2, NOS 2A, NOS, Nos II, NOS type II, Nos2, NOS2A, NOS2_HUMAN.
Background: Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains. Nitric oxide synthase is expressed in liver, macrophages, hepatocytes, synoviocytes, stimulated glial cells and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time. Human iNOS is regulated by calcium/calmodulin (in contrast with mouse NOS2).
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基因ID
- 4843
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UniProt
- P35228
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途径
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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