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RNF111 抗体 (AA 851-950) (Cy7)

This Cy7-conjugated 兔 多克隆 anti-RNF111 antibody specifically detects RNF111 in IF (cc) 和 IF (p). The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN6985823
发货至: 中国
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Quick Overview for RNF111 抗体 (AA 851-950) (Cy7) (ABIN6985823)

抗原

See all RNF111 抗体
RNF111 (Ring Finger Protein 111 (RNF111))

适用

  • 35
  • 32
  • 22
小鼠, 大鼠

宿主

  • 45
  • 4

克隆类型

  • 47
  • 2
多克隆

标记

  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF111 antibody is conjugated to Cy7

应用范围

  • 21
  • 19
  • 12
  • 12
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 851-950

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Sheep,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RNF111

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    RNF111 (Ring Finger Protein 111 (RNF111))

    别名

    RNF111

    背景

    Synonyms: ARK, Arkadia, DKFZp313E0731, DKFZp686H1966, DKFZp761D081, E3 ubiquitin protein ligase Arkadia, FLJ38008, Ring finger protein 111, RNF 111, RN111_HUMAN.

    Background: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

    基因ID

    54778

    UniProt

    Q6ZNA4
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