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IGFBP4 抗体 (AA 181-254) (Cy7)

IGFBP4 适用: 小鼠, 大鼠 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN6985791
发货至: 中国
  • 抗原 See all IGFBP4 抗体
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    抗原表位
    • 14
    • 11
    • 8
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-254
    适用
    • 55
    • 36
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 61
    • 16
    • 1
    克隆类型
    • 63
    • 15
    多克隆
    标记
    • 43
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGFBP4 antibody is conjugated to Cy7
    应用范围
    • 72
    • 41
    • 29
    • 12
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Cow,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human IGFBP4
    亚型
    IgG
    Top Product
    Discover our top product IGFBP4 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    别名
    IGFBP4 (IGFBP4 产品)
    背景

    Synonyms: Insulin-like Growth Factor Binding Protein 4, BP 4, BP4, HT29 IGFBP, IBP 4, IBP4, IGF binding protein 4, IGFBP 4, IBP4_HUMAN.

    Background: Insulin like growth factor binding protein 4 (IGFBP4) is produced from a DNA sequence encoding the human IGFBP4 protein. Mature human IGFBP4 has a calculated molecular mass of approximately 26 kDa. Due to glycosylation, the recombinant protein migrates as a 32 kDa and 25 kDa protein under reducing and non reducing conditions, respectively. Human IGFBP4 has a potential N-linked glycosylation site and shares approximately 90 % amino acid sequence identity with both mouse and rat IGFBP4. IGFBP4 is a member of the superfamily of insulin-like growth factor (IGF) binding proteins which include six high affinity IGF binding proteins (IGFBP) and at least four low affinity binding proteins referred to as IGFBP related proteins (IGFBPrP). IGFBP4 functions as an inhibitor of IGF action and its main function may be to protect cells from overstimulation by IGFs or to allow activation of alternate transmembrane signaling pathways that are inhibited by IGF exposure. IGFBP4 is expressed in multiple tissues including adrenal, testis, spleen, heart, lung, kidney, liver, stomach, hypothalamus, and brain cortex.

    基因ID
    3487
    UniProt
    P22692
    途径
    WNT signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
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