EDC4 抗体 (AA 1-100) (Cy5.5)
Quick Overview for EDC4 抗体 (AA 1-100) (Cy5.5) (ABIN6984965)
抗原
See all EDC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EDC4
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亚型
- IgG
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anti-Enhancer of mRNA Decapping 4 (EDC4) (AA 753-952) antibody
EDC4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (AA 1302-1401) antibodyEDC4 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (AA 1-1401) antibodyEDC4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (C-Term) antibodyEDC4 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (AA 74-123) antibodyEDC4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (AA 800-1100) antibodyEDC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (N-Term) antibodyEDC4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of mRNA Decapping 4 (EDC4) (N-Term) antibodyEDC4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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别名
- EDC4
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背景
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Synonyms: autoantigen, Autoantigen Ge 1, Autoantigen Ge-1, Autoantigen Ge1, Autoantigen RCD 8, Autoantigen RCD-8, Autoantigen RCD8, edc4, EDC4_HUMAN, Enhancer of mRNA decapping 4, Enhancer of mRNA-decapping protein 4, Ge 1, Hedls, Human enhancer of decapping large subunit, RCD 8.
Background: The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.
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基因ID
- 23644
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UniProt
- Q6P2E9
抗原
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