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CD163 抗体 (AA 101-200) (Cy5)

The 兔 多克隆 anti-CD163 antibody is suitable to detect CD163 in samples from 人. It has been validated for WB 和 FACS.
产品编号 ABIN6984725
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD163 抗体 (AA 101-200) (Cy5) (ABIN6984725)

抗原

See all CD163 抗体
CD163

适用

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宿主

  • 129
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克隆类型

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多克隆

标记

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This CD163 antibody is conjugated to Cy5

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    AA 101-200

    交叉反应

    预测反应

    Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CD163.

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CD163

    别名

    CD163

    背景

    Synonyms: Scavenger receptor cysteine-rich type 1 protein M130, CD163, sCD163, M130

    Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

    基因ID

    9332

    UniProt

    Q86VB7
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