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MAP2 抗体 (pThr1613, pThr1619) (Cy5)

This anti-MAP2 antibody is a 兔 多克隆 antibody detecting MAP2 in IF (cc) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6984242
发货至: 中国

Quick Overview for MAP2 抗体 (pThr1613, pThr1619) (Cy5) (ABIN6984242)

抗原

See all MAP2 抗体
MAP2 (Microtubule-Associated Protein 2 (MAP2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MAP2 antibody is conjugated to Cy5

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pThr1613, pThr1619

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthesised phosphopeptide derived from human MAP2 around the phosphorylation site of Thr1613 and Thr1619

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MAP2 (Microtubule-Associated Protein 2 (MAP2))

    别名

    MAP2

    背景

    Synonyms: MAP2(Phospho Thr1613/1619), MAP2 (phospho Thr1613/1619), p-MAP2 (phospho Thr1613/1619), MAP2(Phospho Thr1613/1619), MAP2(Phospho-Thr1613/1619), p-MAP2(Phospho-Thr1613/1619), DKFZp686I2148, Dendrite specific MAP, DKFZp686I2148, MAP 2, MAP-2, MAP2, MAP2_HUMAN, MAP2A, MAP2B, MAP2C, Microtubule associated protein 2, Microtubule-associated protein 2, Mtap 2.

    Background: MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2, two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.

    基因ID

    4133

    UniProt

    P11137
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