RRAGA + RRAGB (AA 231-313) 抗体 (Cy5)
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北京 101111
Quick Overview for RRAGA + RRAGB (AA 231-313) 抗体 (Cy5) (ABIN6984089)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-313
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RRAGA and RRAGB
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RRAGA + RRAGB
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背景
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Synonyms: FIP1, RAGA, FIP-1, RRAGB, Adenovirus E3 14.7 kDa-interacting protein 1, Rag A, RAg B, RagA, RAGB, Ras related GTP binding protein A, RRAGA_HUMAN, Ras-related GTP binding A? GTP-binding protein ragB, Rag B, RagB, Ras-related GTP-binding protein B, RRAGB, RRAGB_HUMAN..
Background: Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
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基因ID
- 10670
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UniProt
- Q7L523
抗原
-
