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PSME3 抗体 (AA 181-254) (Biotin)

This anti-PSME3 antibody is a 兔 多克隆 antibody detecting PSME3 in IHC (p). Suitable for 大鼠.
产品编号 ABIN6982847
发货至: 中国

Quick Overview for PSME3 抗体 (AA 181-254) (Biotin) (ABIN6982847)

抗原

See all PSME3 抗体
PSME3

适用

  • 48
  • 21
  • 17
  • 9
  • 7
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
大鼠

宿主

  • 42
  • 8

克隆类型

  • 44
  • 6
多克隆

标记

  • 33
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
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  • 1
This PSME3 antibody is conjugated to Biotin

应用范围

  • 37
  • 20
  • 15
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  • 6
  • 2
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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 181-254

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PSME3

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PSME3

    别名

    PSME3

    背景

    Synonyms: PA28G, 11S regulator complex gamma subunit, 11S regulator complex subunit gamma, Activator of multicatalytic protease subunit 3, Ki antibody Ki antigen, Ki nuclear autoantigen, Ki, PA28 gamma, PA28 gamma, PA28gamma, Proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki), Proteasome (prosome, macropain) activator subunit 3, Proteasome activator 28 gamma, Proteasome activator 28 subunit gamma, Proteasome activator complex subunit 3, Proteasome activator subunit 3, PSME3, PSME3_HUMAN,

    Background: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).

    基因ID

    10197

    UniProt

    P61289

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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