HUS1 抗体 (AA 51-150) (Biotin)
Quick Overview for HUS1 抗体 (AA 51-150) (Biotin) (ABIN6982666)
抗原
See all HUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HUS1
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
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别名
- HUS1
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背景
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Synonyms: Checkpoint protein HUS1, hHUS1, HUS1 (S. pombe) checkpoint homolog, Hus1, HUS1 checkpoint homolog (S. pombe), HUS1 Checkpoint Protein, HUS1 protein, HUS1+ - like protein, HUS1_HUMAN, Hydroxyurea-sensitive 1, S. pombe, homolog of.
Background: The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
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基因ID
- 3364
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UniProt
- O60921
抗原
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