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C5 抗体 (AA 678-751) (Biotin)

This anti-C5 antibody is a 兔 多克隆 antibody detecting C5 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN6982560
发货至: 中国

Quick Overview for C5 抗体 (AA 678-751) (Biotin) (ABIN6982560)

抗原

See all C5 抗体
C5 (Complement Component 5 (C5))

适用

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宿主

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克隆类型

  • 125
  • 20
多克隆

标记

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This C5 antibody is conjugated to Biotin

应用范围

  • 81
  • 50
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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 21
    • 15
    • 15
    • 12
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 678-751

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human C5a anaphylatoxin

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    C5 (Complement Component 5 (C5))

    别名

    C5a anaphylatoxin

    背景

    Synonyms: Anaphylatoxin C5a, C5, Complement C5, Complement C5 precursor, Complement component 5, CPAMD4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, CO5_HUMAN.

    Background: The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].

    基因ID

    727

    UniProt

    P01031

    途径

    Complement System, Carbohydrate Homeostasis
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