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C5 抗体 (AA 51-150) (Biotin)

This anti-C5 antibody is a 兔 多克隆 antibody detecting C5 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN6982559
发货至: 中国

Quick Overview for C5 抗体 (AA 51-150) (Biotin) (ABIN6982559)

抗原

See all C5 抗体
C5 (Complement Component 5 (C5))

适用

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宿主

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克隆类型

  • 125
  • 20
多克隆

标记

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This C5 antibody is conjugated to Biotin

应用范围

  • 81
  • 50
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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 22
    • 15
    • 14
    • 12
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Complement C5 beta chain

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    C5 (Complement Component 5 (C5))

    别名

    Complement C5 beta chain

    背景

    Synonyms: Anaphylatoxin C5a, C5, Complement C5, Complement C5 precursor, Complement component 5, CPAMD4, CO5_HUMAN.

    Background: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
    Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).

    基因ID

    727

    UniProt

    P01031

    途径

    Complement System, Carbohydrate Homeostasis
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