KDM1B 抗体 (AA 51-150) (AbBy Fluor® 647)
Quick Overview for KDM1B 抗体 (AA 51-150) (AbBy Fluor® 647) (ABIN6980533)
抗原
See all KDM1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LSD2 / AOF1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
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别名
- LSD2 / AOF1
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背景
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Synonyms: LSD2 / AOF1, KDM1B, amine oxidase (flavin containing) domain 1, amine oxidase, flavin containing 1, AOF1, bA204B7.3, C6orf193, dJ298J15.2, Flavin-containing amine oxidase domain-containing protein 1, FLJ33898, FLJ34109, FLJ43328, KDM1B, KDM1B_HUMAN, LSD2, lysine (K)-specific demethylase 1B, Lysine-specific demethylase 2, Lysine-specific histone demethylase 1B, Lysine-specific histone demethylase 2.
Background: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.
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基因ID
- 221656
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UniProt
- Q8NB78
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途径
- Warburg Effect
抗原
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