GAPDH 抗体 (AbBy Fluor® 594)
Quick Overview for GAPDH 抗体 (AbBy Fluor® 594) (ABIN6979694)
抗原
See all GAPDH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
- 
    
- 
                                            
交叉反应
 - 人, 小鼠, Pig, 大鼠
 - 
                                            
纯化方法
 - Purified by Protein G.
 - 
                                            
免疫原
 - KLH conjugated synthetic peptide derived from human GAPDH
 - 
                                            
亚型
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - FCM 1:20-100
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
浓度
 - 1 μg/μL
 - 
                                            
缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
 - 
                                            
储存液
 - ProClin
 - 
                                            
注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
 - 
                                            
储存条件
 - -20 °C
 - 
                                            
储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
 - 
                                            
有效期
 - 12 months
 
 - 
                                            
 - 
    
- GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
 - 
                                            
别名
 - GAPDH
 - 
                                            
背景
 - 
                        
Synonyms: Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, GAPD, CDABP0047, OK/SW-cl.12
Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
 - 
                                            
基因ID
 - 2597
 - 
                                            
UniProt
 - P04406
 
抗原
 -