PLIN1 抗体 (AA 331-430) (AbBy Fluor® 555)
Quick Overview for PLIN1 抗体 (AA 331-430) (AbBy Fluor® 555) (ABIN6978085)
抗原
See all PLIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-430
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IFNAR2
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亚型
- IgG
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应用备注
- FCM 1:20-100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PLIN1 (Perilipin 1 (PLIN1))
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别名
- Perilipin 1
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背景
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Synonyms: Lipid droplet associated protein, Lipid droplet-associated protein, PERI, Perilipin, Perilipin-1, Perilipin 1, PerilipinA, Perilipin-A, PLIN, PLIN1, PLIN1_HUMAN.
Background: Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 26 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.
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基因ID
- 5346
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UniProt
- O60240
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途径
- Lipid Metabolism
抗原
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