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KDM1B 抗体 (AA 51-150) (AbBy Fluor® 488)

This anti-KDM1B antibody (ABIN6978018) is a Rabbit Polyclonal antibody detecting KDM1B in IF (cc), IF (p). Suitable for Mouse, Rat.
产品编号 ABIN6978018
发货至: 中国

Quick Overview for KDM1B 抗体 (AA 51-150) (AbBy Fluor® 488) (ABIN6978018)

抗原

See all KDM1B 抗体
KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

适用

  • 34
  • 22
  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 40
  • 9

克隆类型

  • 35
  • 14
多克隆

标记

  • 20
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KDM1B antibody is conjugated to AbBy Fluor® 488

应用范围

  • 22
  • 22
  • 12
  • 12
  • 9
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-150

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LSD2 / AOF1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

    别名

    LSD2 / AOF1

    背景

    Synonyms: LSD2 / AOF1, KDM1B, amine oxidase (flavin containing) domain 1, amine oxidase, flavin containing 1, AOF1, bA204B7.3, C6orf193, dJ298J15.2, Flavin-containing amine oxidase domain-containing protein 1, FLJ33898, FLJ34109, FLJ43328, KDM1B, KDM1B_HUMAN, LSD2, lysine (K)-specific demethylase 1B, Lysine-specific demethylase 2, Lysine-specific histone demethylase 1B, Lysine-specific histone demethylase 2.

    Background: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.

    基因ID

    221656

    UniProt

    Q8NB78

    途径

    Warburg Effect
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