ZEB1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for ZEB1 抗体 (N-Term) (ABIN6972920)
抗原
See all ZEB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
产品特性
- ZEB1 (Zinc finger E-box-binding homeobox 1, NIL-2-A zinc finger protein Negative regulator of IL2, NIL-2-A, Transcription factor 8, TCF-8) is a POU domain DNA-binding transcriptional regulator that inhibits the expression of E-cadherin and other epithelial genes central to adhesion and epithelial polarity. ZEB1 induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. ZEB1 positively regulates neuronal differentiation and it represses RCOR1 transcription activation during neurogenesis. Defects in ZEB1 are the cause of posterior polymorphous corneal dystrophy type 3 (PPCD3). ZEB1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
-
纯化方法
- Affinity Purified
-
免疫原
- This ZEB1 antibody was raised against a peptide derived from the N-terminal region of human ZEB1.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
-
- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
-
别名
- ZEB1
-
分子量
- 200 kDa
-
NCBI登录号
- NP_110378
-
途径
- Regulation of Muscle Cell Differentiation
抗原
-