KDM1B 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for KDM1B 抗体 (N-Term) (ABIN6972250)
抗原
See all KDM1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
产品特性
- KDM1B / LSD2 (Lysine (K)-Specific Demethylase 1B / Lysine-Specific Histone Demethylase 2) is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (By similarity). KDM1B / LSD2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.
-
纯化方法
- Affinity Purified
-
免疫原
- This antibody was raised against a peptide within the N-terminal region of mouse KDM1B / LSD2.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
-
- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
-
别名
- KDM1B / LSD2
-
分子量
- 93 kDa
-
NCBI登录号
- NP_758466
-
途径
- Warburg Effect
抗原
-