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Histone H2B 抗体 (acLys15)

This anti-Histone H2B antibody is a 兔 多克隆 antibody detecting Histone H2B in WB. Suitable for 人.
产品编号 ABIN6971809
发货至: 中国

Quick Overview for Histone H2B 抗体 (acLys15) (ABIN6971809)

抗原

See all Histone H2B 抗体
Histone H2B

适用

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宿主

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克隆类型

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多克隆

标记

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This Histone H2B antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    acLys15

    产品特性

    Histone H2B is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression. Acetylation of Lys15 is a histone onco-modification candidate as it has been found to be a property of non-dying cells. Histone H2BK15ac antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples, but it is predicted that it will react with a wide range of sample types.

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a peptide including acetyl-lysine 15 of human histone H2B.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    Histone H2B

    分子量

    15 kDa

    NCBI登录号

    NP_003512
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