H2AFV 抗体 (C-Term)
Quick Overview for H2AFV 抗体 (C-Term) (ABIN6971793)
抗原
See all H2AFV 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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产品特性
- The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H2A.Z (H2AZ, H2AFZ) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle.In Drosophila, the H2A variant corresponding to H2AZ is H2Av. H2Av is an essential protein in Drosophila and has been implicated in both activation and repression of transcription. H2Av is localized to centromeric heterochromatin in Drosophila and flies lacking H2Av have reduced levels of heterochromatin components at the centromeres. However, H2Av nucleosome distribution throughout the rest of the Drosophila genome correlates with genes that have an open and uniform chromatin architecture at promoter regions. Histone H2Av antibody (mAb) (Clone 10E9.D1) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Drosophila samples.
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against a peptide in the C-terminus of the Drosophila melanogaster Histone variant H2Av.
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亚型
- IgG2a
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anti-H2A Histone Family, Member V (H2AFV) (AA 1-128) antibody
H2AFV 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member V (H2AFV) (AA 1-128) antibodyH2AFV 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-H2A Histone Family, Member V (H2AFV) (AA 3-128) antibodyH2AFV 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member V (H2AFV) (AA 1-129) antibodyH2AFV 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-H2A Histone Family, Member V (H2AFV) (N-Term) antibodyH2AFV 适用: 人, Drosophila melanogaster, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠, 绵羊, 斑马鱼, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member V (H2AFV) antibodyH2AFV 适用: Drosophila melanogaster ELISA, WB, ChIP 宿主: 小鼠 Monoclonal unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- H2AFV (H2A Histone Family, Member V (H2AFV))
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别名
- Histone H2Av
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分子量
- 15 kDa
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NCBI登录号
- NP_524519
抗原
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