H2AFZ 抗体 (C-Term)
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北京 101111
Quick Overview for H2AFZ 抗体 (C-Term) (ABIN6971773)
抗原
See all H2AFZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression. Histone H2A.Z (H2AZ, H2AFZ) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle. H2A.Z is acetylated at multiple lysine residues in its amino terminus, which may enable H2A.Z to function as an insulator of chromatin domains. Histone H2A.Z antibody (pAb) (H2AZ) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Dot blot, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human samples, but it is predicted that it will react with a wide range of sample types.
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纯化方法
- Protein A Chromatography
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免疫原
- This Histone H2A.Z antibody was raised against a peptide derived from the C-terminus of human histone H2A.Z.
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亚型
- IgG
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anti-H2A Histone Family, Member Z (H2AFZ) (H2A.ZK4ac) antibody
H2AFZ 适用: 人 WB, ELISA, ICC, IF, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (H2A.ZK7ac) antibodyH2AFZ 适用: 人 WB, ELISA, ICC, IF, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibodyH2AFZ 适用: 人 WB, ICC, IF, ChIP, IP, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (N-Term) antibodyH2AFZ 适用: 人 WB, ICC, IF, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibodyH2AFZ 适用: 人 WB, IF, ChIP, ChIP-seq, DB, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (H2A.ZK4me1) antibodyH2AFZ 适用: 人 ELISA, ICC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) antibodyH2AFZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) antibodyH2AFZ 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 7G8 unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (AA 2-128) antibodyH2AFZ 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (AA 1-128) antibodyH2AFZ 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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别名
- Histone H2A.Z
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分子量
- 14 kDa
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NCBI登录号
- NP_002097
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途径
- Telomere Maintenance
抗原
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