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H2AFJ 抗体 (AA 122-129)

This anti-H2AFJ antibody is a 兔 多克隆 antibody detecting H2AFJ in WB 和 DB. Suitable for 人 和 小鼠.
产品编号 ABIN6971761
发货至: 中国

Quick Overview for H2AFJ 抗体 (AA 122-129) (ABIN6971761)

抗原

See all H2AFJ 抗体
H2AFJ (H2A Histone Family, Member J (H2AFJ))

适用

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人, 小鼠

宿主

  • 38

克隆类型

  • 38
多克隆

标记

  • 15
  • 6
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  • 1
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This H2AFJ antibody is un-conjugated

应用范围

  • 29
  • 16
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Western Blotting (WB), Dot Blot (DB)
  • 抗原表位

    • 9
    • 7
    • 5
    • 3
    • 1
    • 1
    AA 122-129

    产品特性

    Histone H2A is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, and is responsible for establishing higher-order chromatin structure. Histone H2A.J is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. Histone H2A.J, which is found only in mammals, is shown to be associated with senescence, accumulating in senescent fibroblasts and promoting expression of inflammatory genes. Therefore, H2A.J may contribute to chronic inflammation and age-related diseases. Histone H2A.J antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot and Western blot, it has been shown to react with Human and Mouse samples.

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a peptide comprising amino acids 122-129 of human Histone H2A.J.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    H2AFJ (H2A Histone Family, Member J (H2AFJ))

    别名

    Histone H2A.J

    NCBI登录号

    NP_808760
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