H2AFJ 抗体 (AA 122-129)
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北京 101111
Quick Overview for H2AFJ 抗体 (AA 122-129) (ABIN6971761)
抗原
See all H2AFJ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 122-129
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产品特性
- Histone H2A is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, and is responsible for establishing higher-order chromatin structure. Histone H2A.J is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. Histone H2A.J, which is found only in mammals, is shown to be associated with senescence, accumulating in senescent fibroblasts and promoting expression of inflammatory genes. Therefore, H2A.J may contribute to chronic inflammation and age-related diseases. Histone H2A.J antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot and Western blot, it has been shown to react with Human and Mouse samples.
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a peptide comprising amino acids 122-129 of human Histone H2A.J.
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亚型
- IgG
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anti-H2A Histone Family, Member J (H2AFJ) (AA 2-129) antibody
H2AFJ 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member J (H2AFJ) antibodyH2AFJ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member J (H2AFJ) (AA 13-62) antibodyH2AFJ 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- H2AFJ (H2A Histone Family, Member J (H2AFJ))
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别名
- Histone H2A.J
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NCBI登录号
- NP_808760
抗原
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