GLI1 抗体 (C-Term)
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北京 101111
Quick Overview for GLI1 抗体 (C-Term) (ABIN6971684)
抗原
See all GLI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- GLI1 (Glioma-associated oncogene 1) is a zinc finger transcription factor and oncogene. GLI1 is part of the hedgehog signaling pathway, but is also activated in response to TGF-b signaling as well. GLI1 activates transcription of a number of genes that promote cell cycle progression. GLI1 is overexpressed as a result of constitutive activation of hedgehog signaling, which plays a role in the initiation of cancer. GLI1 also promotes self-renewal of neural stem cells. GLI1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This GLI1 antibody was raised against a peptide within the C-terminal region of human GLI1.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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别名
- GLI1
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分子量
- 120 kDa
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NCBI登录号
- NP_005260
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途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
抗原
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