电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

EZH1 抗体 (N-Term)

This anti-EZH1 antibody is a 兔 多克隆 antibody detecting EZH1 in WB. Suitable for 小鼠.
产品编号 ABIN6971640
发货至: 中国

Quick Overview for EZH1 抗体 (N-Term) (ABIN6971640)

抗原

See all EZH1 抗体
EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

适用

  • 71
  • 40
  • 30
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
小鼠

宿主

  • 68
  • 4
  • 1

克隆类型

  • 69
  • 4
多克隆

标记

  • 42
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EZH1 antibody is un-conjugated

应用范围

  • 58
  • 33
  • 29
  • 13
  • 13
  • 12
  • 11
  • 11
  • 9
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    产品特性

    EZH1 (Enhancer Of Zeste Homolog 1 ) is a Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. EZH1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a peptide within the N-terminal region of human EZH1.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

    别名

    EZH1

    分子量

    100 kDa

    NCBI登录号

    NP_001982
You are here:
Chat with us!